Allogeneic bone marrow transplantation with reduced intensity conditioning for chronic granulomatous disease complicated by invasive Aspergillus infection
Identifieur interne : 001D77 ( Main/Exploration ); précédent : 001D76; suivant : 001D78Allogeneic bone marrow transplantation with reduced intensity conditioning for chronic granulomatous disease complicated by invasive Aspergillus infection
Auteurs : Jairam Sastry [Australie] ; Alyson Kakakios [Australie] ; Heidi Tugwell [Australie] ; Peter J. Shaw [Australie]Source :
- Pediatric Blood & Cancer [ 1545-5009 ] ; 2006-09.
Abstract
Chronic granulomatous disease (CGD) is a rare disorder characterized by recurrent infections, often resulting in impaired quality of life and death. Allogeneic BMT provides a definitive cure for CGD, but carries a significant risk of mortality and morbidity. The risk is higher for those who have invasive fungal infection prior to transplant. Reduced intensity conditioning (RIC) is associated with less toxicity from the conditioning agents and may provide an alternative option for all non‐malignant diseases. We report a case of successful allogeneic BMT after RIC for a case of X‐linked CGD complicated by severe invasive aspergillosis (IA). Pediatr Blood Cancer 2006;47:327–329. © 2006 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/pbc.20865
Affiliations:
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Shaw</name><name sortKey="Shaw, Peter J" sort="Shaw, Peter J" uniqKey="Shaw P" first="Peter J." last="Shaw">Peter J. Shaw</name><name sortKey="Tugwell, Heidi" sort="Tugwell, Heidi" uniqKey="Tugwell H" first="Heidi" last="Tugwell">Heidi Tugwell</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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